Can factors affecting complication rates for ureteric re-implantation be predicted? Use of the modified Clavien
Evren Suer1, Cihat Ozcan, Murat Mermerkaya
1Department of Urology, Ibn-i Sina Hospital, Ankara University, Ankara, Turkey.
Insights
Ureteric re-implantation is effective for VUR treatment. Key predictors of complications include voiding dysfunction, megaureters, and duplex systems, identified using the modified Clavien classification system.
Area of Science:
- Pediatric Urology
- Surgical Complications
- Reconstructive Surgery
Background:
- Ureteric re-implantation is a surgical procedure for vesico-ureteric reflux (VUR) and other conditions.
- Assessing postoperative complications is crucial for patient outcomes.
- The modified Clavien classification system (MCCS) offers a standardized method for grading surgical complications.
Purpose of the Study:
- To identify preoperative factors predicting postoperative complications after ureteric re-implantation in children.
- To utilize the modified Clavien classification system (MCCS) for complication assessment.
Main Methods:
- A retrospective study of 383 children undergoing ureteric re-implantation between 2002 and 2011.
- Complications were classified using the MCCS.
- Univariate and multivariate analyses were performed to identify predictive factors for complications.
Main Results:
- Complications occurred in 19.8% of patients, with MCCS grades I, II, and III reported.
- Univariate analysis identified hydronephrosis, obstructing megaureters, tailoring-tapering-folding procedures, voiding dysfunction, and duplex systems as significant predictors.
- Multivariate analysis confirmed refractory voiding dysfunction, tailoring-tapering-folding procedures, obstructing megaureters (>9mm), and duplex systems as significant predictors of complications.
Conclusions:
- Ureteric re-implantation is a viable treatment for select VUR patients.
- Refractory voiding dysfunction, specific surgical techniques (tailoring-tapering-folding), obstructing megaureters, and duplex systems are key predictors of postoperative complications.
- Standardized complication grading systems like MCCS are essential for comparing surgical outcomes.
Objective:
To determine preoperative predictive factors of postoperative complications of ureteric re-implantation in children by using the modified Clavien classification system (MCCS), which has been widely used for complication rating of surgical procedures.
Patients And Methods:
In all, 383 children who underwent ureteric re-implantation for vesico-ureteric reflux (VUR) and obstructing megaureters between 2002 and 2011 were included in the study. Intravesical and extravesical ureteric re-implantations were performed in 338 and 45 children, respectively. Complications were evaluated according to the MCCS. Univariate and multivariate analyses were used to determine predictive factors affecting complication rates.
Results:
In all, 247 girls and 136 boys were studied. The mean (sd) age was 46 (25) months and the mean (sd) follow-up was 49.4 (27.8) months. The mean (sd) hospitalisation time was 4.7 (1.6) days. Complications occurred in 76 (19.8%) children; 34 (8.9%) were MCCS grade I, 22 (5.7%) were grade II and 20 (5.2%) were grade III. Society of Fetal Urology (SFU) grade 3-4 hydronephrosis, obstructing megaureters, a tailoring-tapering and folding procedure, refractory voiding dysfunction and a duplex system were statistically significant predictors of complications on univariate analysis. Prior injection history, paraureteric diverticula, stenting, gender, age, operation technique (intra vs extravesical) were not significant predictors of complications. In the multivariate analysis refractory voiding dysfunction, a tailoring-tapering and folding procedure, obstructing megaureters (diameter of >9 mm) and a duplex system were statistically significant predictors of complications.
Conclusion:
Ureteric re-implantation remains a valid option for the treatment of certain patients with VUR. Refractory voiding dysfunction, a tailoring-tapering and folding procedure, obstructing megaureters (diameter of >9 mm) and associated duplex systems were the main predictive factors for postoperative complications. Use of a standardised complication grading system, such as the MCCS, should be encouraged to allow the valid comparison of complication rates between series.
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