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Published on: November 7, 2017
Cardiorenal syndrome
Claudio Ronco1, Luca Di Lullo2
1International Renal Research Institute, S. Bortolo Hospital, Viale F. Ridolfi 37, Vicenza 36100, Italy.
Insights
Cardiorenal syndrome (CRS) involves heart and kidney dysfunction. This review details the pathophysiology, diagnosis, treatment, and outcomes of five CRS types, aiding clinical management.
Area of Science:
- Nephrology
- Cardiology
- Internal Medicine
Background:
- Cardiorenal syndrome (CRS) encompasses complex heart and kidney interactions.
- Existing classifications categorize CRS based on the primary organ affected (cardiac or renal) and disease onset (acute or chronic).
Purpose of the Study:
- To provide a comprehensive overview of the pathophysiology, diagnosis, treatment, and outcomes of the five distinct types of Cardiorenal Syndrome.
- To elucidate the mechanisms and clinical implications of CRS subtypes, including those secondary to systemic diseases.
Main Methods:
- Literature review and synthesis of existing research on Cardiorenal Syndrome.
- Analysis of classification systems and clinical data pertaining to CRS.
Main Results:
- CRS is categorized into cardiorenal and renocardiac types, further divided into acute and chronic forms.
- A fifth category of CRS addresses cardiorenal involvement secondary to systemic diseases.
- The article discusses the pathophysiology, diagnostic approaches, therapeutic strategies, and prognostic factors for each CRS type.
Conclusions:
- Understanding the distinct types of CRS is crucial for effective clinical management.
- Integrated approaches addressing both cardiac and renal aspects are essential for improving patient outcomes in Cardiorenal Syndrome.
Abstract:
Cardiorenal syndrome (CRS) includes a broad spectrum of diseases within which both the heart and kidneys are involved, acutely or chronically. An effective classification of CRS in 2008 essentially divides CRS in two main groups, cardiorenal and renocardiac CRS, based on primum movens of disease (cardiac or renal); both cardiorenal and renocardiac CRS are then divided into acute and chronic, according to onset of disease. The fifth type of CRS integrates all cardiorenal involvement induced by systemic disease. This article addresses the pathophysiology, diagnosis, treatment, and outcomes of the 5 distinct types of CRS.
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