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[Frameless stereotactic biopsy: diagnostic yield and complications]
Maria Castle1, Edinson Nájera1, Nicolas Samprón1
1Departamento de Neurocirugía, Hospital Universitario Donostia, San Sebastián, Guipúzcoa, España.
Neurocirugia (Asturias, Spain)
|March 25, 2014
Summary
Frameless stereotactic biopsy offers high diagnostic yield, but superficial lesions under 2cm may reduce accuracy. Complication rates were not increased after repeat biopsies.
Area of Science:
- Neurosurgery
- Neuroradiology
- Oncologic Imaging
Background:
- Frameless stereotactic biopsy is a minimally invasive technique for obtaining tissue samples from brain lesions.
- Optimizing the diagnostic yield and understanding complication risks are crucial for patient management.
Purpose of the Study:
- To evaluate factors influencing the diagnostic yield of frameless stereotactic biopsy.
- To assess the complication rate associated with this procedure.
Main Methods:
- Retrospective analysis of 75 frameless stereotactic biopsies performed between July 2008 and December 2011.
- Studied variables included lesion size, distance to cortex, contrast uptake, and location.
Main Results:
- Overall diagnostic yield was 97.1%.
- Lesions >19mm showed higher sensitivity (95.2%) than those within 17mm of the cortex (74.6%).
- Complications occurred in 10% of patients after the first biopsy, with no increase after a second biopsy.
Conclusions:
- Diagnostic yield is reduced for lesions <2cm and those located superficially.
- Frameless stereotactic biopsy is a safe procedure, even with repeat sampling.
