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Updated: Aug 14, 2026

Basic Research in Plasma Medicine - A Throughput Approach from Liquids to Cells
Published on: November 17, 2017
Therapeutic applications of plasma exchange
C O Savage1, I Banks, C D Pusey
1Hammersmith Hospital, London.
Therapeutic plasma exchange is a procedure used for various conditions involving harmful macromolecules. This review covers its practicalities and evaluates the evidence supporting its effectiveness.
Area of Science:
- Medical Science
- Clinical Practice
- Immunology
Background:
- Therapeutic plasma exchange (TPE) is employed for diseases where pathogenic macromolecules circulate in the blood.
- Understanding the role of these macromolecules is crucial for TPE application.
Purpose of the Study:
- To review the practical aspects of performing therapeutic plasma exchange.
- To critically assess the existing evidence for the clinical benefits of TPE.
Main Methods:
- Literature review of TPE procedures.
- Analysis of clinical studies and case reports on TPE efficacy.
Main Results:
- TPE is a versatile procedure applicable to diverse pathological conditions.
- Evidence for TPE benefit varies across different disorders, requiring careful consideration.
Conclusions:
- Therapeutic plasma exchange is a valuable tool in managing specific diseases.
- Further research is needed to solidify the evidence base for TPE in many indications.
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