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Platelet derived growth factor (PDGF) and prostaglandins (PGE1, PGI2) as modulators of the atherogenetic process
H Sinzinger1, T Zidek, P Fitscha
1Atherosclerosis Research Group (ASF) Vienna, Austria.
Abstract:
It is concluded that the interaction between platelets, the PDGF- and PG-formation may be of key-importance in human atherosclerosis, not only by regulation of smooth muscle cell proliferation and extracellular matrix production but also in cellular lipid metabolism.