Related Experiment Videos
Diagnosis and differentiation of von Willebrand's disease type II
H Lenk1, I M Nilsson, L Holmberg
1Department of Paediatrics, Karl-Marx-University Leipzig, GDR.
Folia Haematologica (Leipzig, Germany : 1928)
|January 1, 1988
Abstract:
Out of 113 patients with vWD 15 were of type II. The basic test programme included F VIII:C, vWF-Ag, RCF and BT (Ivy). All type II patients had relatively high vWF-Ag and low RCF values. CIEP proved increased anodal migration velocity. IRMA testing of vWF:Ag was showing narrow correlation with RCF. Thrombocyte count was unchanged after DDAVP infusion and RIPA was always diminished. Finally multimeric sizing was done in 6 patients. From the completely diagnosed patients 5 are of type IIA and one seems to have type IIC. Nobody of the 15 had the characteristics of type IIB.