Related Experiment Video
Updated: May 1, 2026
The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
Published on: June 1, 2019
Sentinel lymph node biopsy for cutaneous melanoma: a propos of 144 cases
Petros Konofaos1, Dimitrios Karypidis, Chrisostomos Chrisostomidis
12nd Department of Propedeutic Surgery, of Athens University, "Laiko" General Hospital, Athens, Greece.
Purpose:
The aim of this study was to identify the predictive factors of a positive sentinel lymph node (SLN) in patients with cutaneous malignant melanomas and tumor progression.
Methods:
From October of 2000 to January of 2006, 144 patients with cutaneous malignant melanoma underwent SLN biopsy. Patients were divided into two groups according to the SLN status (positive vs negative) which were compared with regards to patient demographics and primary tumor characteristics.
Results:
In 37 (25.69%) patients SLN biopsy was positive . Nodular melanomas (p=0.047), blood (p=0.010) and lymph (p<0.001) vessel infiltration, mitotic rate (p=0.019) and Breslow thickness (p=0.012) were predictive of a positive SLN biopsy. The overall recurrence, mortality and the overall disease free survival (DFS) rates were 6.25, 1.4 and 93.75, respectively.
Conclusion:
SLN biopsy is the most important predictor of early disease recurrence and survival in patients with cutaneous malignant melanoma. Considering all the examined factors, a positive SLN biopsy is related with Breslow thickness and lymph vessel infiltration.
More Related Videos
05:52Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
Published on: August 19, 2021
08:18Analysis of Lymph Node Volume by Ultra-High-Frequency Ultrasound Imaging in the Braf/Pten Genetically Engineered Mouse Model of Melanoma
Published on: September 8, 2021
