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Updated: May 1, 2026

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Synthesis of sepiapterin-C via hydrolysis of 6-ethynylpteridine
Natural Product Communications
|March 26, 2014
Abstract:
Acid hydrolysis of 6-ethynylpteridine catalyzed by mercury oxide gives 6-acetyl-2-amino-3,4-dihydropteridin-4-one in good yield. Partial reduction of the product with dissolved Al in NH3 solution afforded sepiapterin-C.
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