Differentiation between calcification and hemorrhage in brain tumors using susceptibility-weighted imaging: a pilot
Jatta Berberat1, Rainer Grobholz, Larissa Boxheimer
11 Department of Radiology, Cantonal Hospital Aarau, Tellstrasse, CH-5001 Aarau, Switzerland.
AJR. American Journal of Roentgenology
|March 26, 2014
Abstract
Objective:
Our aim was to develop a robust method to differentiate calcification from hemorrhage in gliomas. Histopathologic examination was performed to validate hemorrhage and calcification.
Conclusion:
Phase images from eleven patients with glioma yielded statistically significant phase-shift values for calcification and hemorrhage compared with normal brain, whereas CT showed substantial overlap of Hounsfield units. Phase image analysis correctly differentiated between intratumoral calcification and hemorrhage in 86% of cases.
