Related Experiment Video
Updated: May 1, 2026
Author Spotlight: Unraveling the Mechanobiology of Tendon Impingement – A Multiaxial Murine Hind Limb Explant Model
Published on: December 8, 2023
Rotator cuff tendon ultrastructure assessment with reduced-orientation dipolar anisotropy fiber imaging
Eric Y Chang1, Nikolaus M Szeverenyi, Sheronda Statum
11 Department of Radiology, VA San Diego Healthcare System, 3350 La Jolla Village Dr, MC 114, San Diego, CA 92161.
Objective:
The anisotropic fibrous structure of collagen can significantly affect MRI signal intensity. Use of this magic angle effect as a contrast mechanism has been previously termed "dipolar anisotropy fiber imaging." The goal of this pilot study was to use a reduced-orientation version of dipolar anisotropy fiber imaging to study rotator cuff tendon internal fiber structure.
Conclusion:
The reduced-orientation dipolar anisotropy fiber imaging technique can be used to delineate the complex contributions and ultrastructure of the rotator cuff.
