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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

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[Real-time three dimensional echocardiography-based evaluation of left ventricular function in children with Kawasaki

Xiao-Xu Chen1, Ling Zhang, Kun Wang

  • 1Department of Physical Diagnosis, Longnan Hospital, Daqing, Heilongjiang 163453, China. 734421258@qq.com.

Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics
|March 26, 2014
PubMed

Insights

Real-time three-dimensional echocardiography (RT-3DE) effectively assesses left ventricular systolic function in children with Kawasaki disease (KD). RT-3DE reveals subtle cardiac changes, even in patients without coronary artery lesions, highlighting its clinical significance.

Area of Science:

  • Pediatric Cardiology
  • Echocardiography
  • Cardiovascular Imaging

Background:

  • Kawasaki disease (KD) can affect left ventricular (LV) systolic function.
  • Assessing LV function in pediatric KD patients is crucial for management.
  • Traditional echocardiography may not fully capture subtle functional changes.

Purpose of the Study:

  • To evaluate the clinical significance of full volume real-time three-dimensional echocardiography (RT-3DE).
  • To assess general and local systolic functions of the left ventricle in children with KD.
  • To compare RT-3DE findings in KD patients with and without coronary artery lesions against healthy controls.

Main Methods:

  • Recruited 73 KD children (40 with, 33 without coronary artery lesions) and 35 healthy controls.
  • Measured left ventricular ejection fraction (LVEF) using M-mode ultrasound and RT-3DE.
  • Generated LV volume-time and segmental speed-time curves for analysis.

Main Results:

  • M-mode LVEF was lower in KD patients with coronary artery lesions compared to others.
  • RT-3DE revealed significant differences in LVEF across the three groups (lesions < no lesions < controls).
  • RT-3DE segmental analysis showed elevated Tmsv values in KD patients, indicating impaired local systolic function, even in those without coronary lesions.

Conclusions:

  • Full volume RT-3DE enables quantitative evaluation of LV function in pediatric KD.
  • RT-3DE demonstrates significant clinical implications for detecting and monitoring cardiac involvement in KD.
  • This advanced imaging technique can identify subtle systolic dysfunction missed by conventional methods.
Abstract

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