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Nine-year follow-up of children with atopic dermatitis by general practitioners
Laurent Misery1, Xavier Ansolabehere, Nathalie Grandfils
1Department of Dermatology, University Hospital of Brest, Brest, France.
Insights
Infants with atopic dermatitis (AD) experience more comorbidities, particularly respiratory and ophthalmic conditions. These children also incur higher medical costs for treatments, though this difference decreases with age.
Area of Science:
- Dermatology
- Pediatrics
- Public Health
Background:
- Atopic dermatitis (AD) is a common chronic inflammatory skin condition in infants.
- The full extent of comorbidities and treatment costs associated with childhood AD in primary care is not well-established.
Purpose of the Study:
- To investigate the frequency of associated comorbidities in infants diagnosed with AD.
- To quantify the treatment costs for patients with AD compared to a control group in a primary care setting.
Main Methods:
- Retrospective cohort study utilizing a longitudinal electronic medical records database in France.
- Matched cohort of 1,163 infants with AD (diagnosed in the first year of life) and 1,163 controls, followed for 9 years.
- Detailed analysis of associated diseases, drug prescriptions, and medical costs.
Main Results:
- Infants with AD exhibited a higher prevalence of comorbidities, notably affecting the respiratory and ophthalmic systems.
- Patients with AD incurred greater healthcare expenditures, including general practitioner consultations and prescribed medications.
- The disparity in medical costs between AD patients and controls diminished as the children aged.
Conclusions:
- Childhood atopic dermatitis is linked to increased comorbidity burden and higher healthcare costs in primary care.
- Early diagnosis and management of AD may be crucial for mitigating long-term health impacts and economic consequences.
Abstract:
The frequency of associated comorbidity and the cost of treatments in patients with atopic dermatitis (AD) followed up in primary care settings are poorly known. We carried out a retrospective cohort study on a longitudinal electronic medical records database of patients consulting a panel of general practitioners in France. All subjects with AD diagnosed during the first year of life were selected and matched with infants without the disease according to sex (1,163 vs. 1,163). Subjects were followed up for 9 years. Associated diseases, drug consumptions and available medical costs were detailed. Comparisons between subjects and controls were carried out. Subjects with AD had more comorbidities than others, especially in respiratory and ophthalmic system organs. The number of prescribed treatments in the field of skin diseases as well as overall medical costs (general practitioner consultations and prescribed drugs) were higher among atopic subjects, but differences were attenuated with age.
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