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Red Si-rhodamine drug conjugates enable imaging in GFP cells
Eunha Kim1, Katherine S Yang, Randy J Giedt
1Center for Systems Biology, Massachusettes General Hospital/Harvard Medical School, 185 Cambridge St, Boston, MA 02114, USA. rweissleder@mgh.harvard.edu.
Abstract:
Here we evaluated a series of Si-derivatized rhodamine (SiR) dyes for their ability to visualize a model drug in live cells. We show that a charge neutral SiR derivative (but not others) can indeed be used to follow the intracellular location of the model therapeutic drug in GFP cells.

