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Normal values for heart rate variability parameters in children 6-8 years of age: the PANIC Study

Santeri Seppälä1, Tomi Laitinen, Mika P Tarvainen

  • 1Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.

Clinical Physiology and Functional Imaging
|March 27, 2014
PubMed

Insights

Reference values for heart rate variability (HRV) parameters were established in children aged 6-8 years. These reference values are applicable to both boys and girls, with 1-minute ECG recordings providing reliable data.

Area of Science:

  • Pediatric Cardiology
  • Autonomic Nervous System Function
  • Biomedical Signal Analysis

Background:

  • Heart rate variability (HRV) is crucial for assessing cardiac autonomic control.
  • Existing HRV research is limited in pediatric populations.
  • Establishing normative HRV data in children is essential.

Purpose of the Study:

  • To define reference values for a comprehensive set of HRV parameters in children.
  • To investigate potential gender-specific differences in HRV.
  • To assess the influence of age, maturity, and anthropometric factors on HRV.

Main Methods:

  • Analyzed electrocardiogram (ECG) recordings from 465 children aged 6-8 years.
  • Utilized 1-minute and 5-minute ECG samples for HRV analysis.
  • Examined gender differences and correlations with anthropometric and developmental factors.

Main Results:

  • No statistically significant gender differences were found in HRV parameters.
  • Reference values were established using percentiles across all children.
  • Age, maturity, height, weight, and BMI-SDS showed minimal confounding effects on HRV parameters.

Conclusions:

  • Unified reference values for HRV parameters are suitable for both boys and girls.
  • While 5-minute ECGs are optimal, 1-minute recordings offer reliable HRV data, particularly for parasympathetic regulation.
  • These findings provide a valuable resource for pediatric autonomic function assessment.
Abstract

Keywords:
HRVautonomic regulationelectrocardiographygenderreference value

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