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COMfort Eye Trial (COMET) results - a non-inferiority, randomized, investigator-masked, two-parallel group, phase III clinical trial, to evaluate the efficacy and safety of a preservative free formulation of latanoprost versus a reference drug (Xalatan®) in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OHT).

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Related Experiment Video

Updated: May 1, 2026

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
05:46

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity

Published on: September 20, 2024

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Current management of presbyopia.

Pandelis A Papadopoulos1, Alexandros P Papadopoulos2

  • 1Ophthalmology Clinic, Athens Metropolitan Hospital, Athens, Greece ; Ophthalmology Department, Slovak Medical University, Bratislava, Slovakia.

Middle East African Journal of Ophthalmology
|March 27, 2014
PubMed
Summary
This summary is machine-generated.

Presbyopia correction surgery aims to restore near vision but faces limitations. Current refractive surgery techniques for presbyopia have challenges impacting widespread adoption.

Keywords:
PresbyopiaSurgical CorrectionTreatment

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Area of Science:

  • Ophthalmology
  • Refractive Surgery
  • Vision Science

Background:

  • Presbyopia, the age-related loss of near focusing ability, affects individuals typically in their fifth decade.
  • Restoring accommodation and correcting presbyopia remain significant challenges in refractive surgery.
  • Surgical interventions targeting the cornea, crystalline lens, and sclera are under investigation for presbyopia correction.

Purpose of the Study:

  • To provide an updated overview of current surgical procedures for presbyopia correction.
  • To critically analyze the limitations and considerations associated with existing presbyopia correction techniques.

Main Methods:

  • Review of current surgical approaches for presbyopia correction.
  • Analysis of reported outcomes, limitations, and complications of these procedures.

Main Results:

  • Various surgical techniques exist for presbyopia, targeting different ocular structures.
  • Significant limitations include visual quality issues, optical distortions, effect regression, and potential complications.
  • Invasive nature and specific side effects like corneal ectasia and impaired distance vision hinder widespread acceptance.

Conclusions:

  • Surgical correction of presbyopia is an evolving field with ongoing research.
  • Current methods face substantial limitations that prevent universal adoption.
  • Further advancements are needed to overcome existing challenges for effective presbyopia surgical correction.