A pilot program for physical exercise promotion in adults with type 1 diabetes: the PEP-1 program
Anne-Sophie Brazeau1, Véronique Gingras, Catherine Leroux
1a Montreal Institute for Clinical Research, 110 Avenue des Pins Ouest, Montreal, QC H2W 1R7, Canada.
Summary
The Physical Exercise Promotion in Type 1 Diabetes (PEP-1) program did not increase total energy expenditure in adults with type 1 diabetes. While cardiorespiratory fitness improved temporarily, long-term benefits were not sustained.
Area of Science:
- Endocrinology
- Exercise Physiology
- Public Health
Background:
- Physical inactivity is prevalent in adults with type 1 diabetes (T1D), often due to barriers like hypoglycemia.
- Addressing physical inactivity is crucial for managing T1D and improving overall health outcomes.
Purpose of the Study:
- To evaluate the efficacy of the Physical Exercise Promotion in Type 1 Diabetes (PEP-1) program compared to an information leaflet.
- To determine the program's impact on total energy expenditure (TEE) and cardiorespiratory fitness in adults with T1D over 12 weeks and 1 year.
Main Methods:
- A pilot randomized trial involving 48 adults with T1D (age 18-65, low physical activity levels).
- Intervention group received 12 weekly sessions of information and physical activity (PA); control group received an information leaflet.
- Total energy expenditure (TEE) measured via motion sensor; peak oxygen uptake assessed at baseline, 12 weeks, and 1 year.
Main Results:
- No significant changes in TEE or glycated hemoglobin (A1c) were observed in either group.
- The PEP-1 intervention group showed a significant increase in peak oxygen uptake after 12 weeks (14%), but this was not sustained at the 1-year follow-up.
- No changes in peak oxygen uptake were noted in the control group.
Conclusions:
- The PEP-1 program may temporarily enhance cardiorespiratory fitness in adults with T1D.
- The observed fitness benefits were not maintained long-term.
- The PEP-1 program did not effectively increase TEE, indicating a need for alternative strategies to combat physical inactivity in this population.
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