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Updated: May 1, 2026
Dissection of the Drosophila Pupal Retina for Immunohistochemistry, Western Analysis, and RNA Isolation
Published on: March 15, 2019
A novel cell death gene acts to repair patterning defects in Drosophila melanogaster
Kentaro M Tanaka1, Aya Takahashi2, Naoyuki Fuse3
1Department of Population Genetics, National Institute of Genetics, Yata 1111, Mishima, Shizuoka, 411-8540, Japan Department of Biological and Medical Sciences, Oxford Brookes University, Gipsy Lane, Oxford, OX3 0BP, United Kingdom fruitfly@kit.ac.jp p0037755@brookes.ac.uk.
Abstract:
Cell death is a mechanism utilized by organisms to eliminate excess cells during development. Here, we describe a novel regulator of caspase-independent cell death, Mabiki (Mabi), that is involved in the repair of the head patterning defects caused by extra copies of bicoid in Drosophila melanogaster. Mabiki functions together with caspase-dependent cell death mechanisms to provide robustness during development.
