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Published on: June 2, 2014
Metabolic syndrome in migraine headache: A case-control study
Mehrzad Salmasi1, Laya Amini1, Shaghayegh Haghjooy Javanmard2
1Isfahan Neurosciences Research Center, Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran.
Metabolic syndrome was not significantly correlated with migraine headaches in this study. However, higher body mass index and waist circumference were more frequent in migraine patients.
Area of Science:
- Neurology
- Endocrinology
- Public Health
Background:
- Previous studies explored the link between metabolic syndrome and migraine.
- No studies have directly compared metabolic syndrome prevalence in migraine patients versus controls.
- Controlling metabolic syndrome may reduce therapeutic resistance in migraine patients.
Purpose of the Study:
- To compare the prevalence of metabolic syndrome in patients with and without migraine headaches.
- To investigate potential correlations between metabolic syndrome and migraine.
Main Methods:
- 200 patients diagnosed with migraine according to International Headache Society criteria were enrolled.
- 200 healthy individuals without migraine served as controls.
- Metabolic syndrome was diagnosed using ATP III criteria in both groups and compared.
Main Results:
- Metabolic syndrome prevalence was 17% in migraine patients and 15% in controls (P = 0.585).
- Body mass index (P = 0.05) and waist circumference (P = 0.03) were significantly more frequent in migraine patients.
Conclusions:
- No significant overall correlation was found between metabolic syndrome and migraine headache.
- Specific metabolic syndrome components, namely higher body mass index and waist circumference, showed a correlation with migraine.
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