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Updated: May 1, 2026

Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients
Published on: April 18, 2025
Can hospital rounds with pocket ultrasound by cardiologists reduce standard echocardiography?
Hashim A Khan1, Nathan E Wineinger2, Poulina Q Uddin3
1Division of Cardiovascular Diseases, Scripps Clinic, Scripps Health, La Jolla, Calif; Scripps Translational Science Institute, La Jolla, Calif.
Insights
Pocket mobile echocardiography offers a cost-effective and accurate alternative to traditional transthoracic echocardiograms for hospitalized patients. This bedside tool, used by cardiology fellows, provides comparable results to formal studies, potentially reducing healthcare costs.
Area of Science:
- Cardiology
- Medical Imaging
- Point-of-Care Diagnostics
Background:
- Hospitalized patients frequently require transthoracic echocardiograms.
- Pocket mobile echocardiography devices offer a potentially useful and cost-effective alternative for bedside use by cardiologists.
Purpose of the Study:
- To compare the accuracy of pocket mobile echocardiography with standard transthoracic echocardiography in hospitalized patients.
- To evaluate the visualizability and accuracy of key echocardiographic parameters using both imaging modalities.
Main Methods:
- A cross-sectional study involving 240 hospitalized patients undergoing both pocket mobile and transthoracic echocardiography.
- Pocket mobile echocardiography was performed and interpreted by cardiology fellows; transthoracic echocardiography was done by skilled ultrasonographers.
- Both imaging groups were blinded to the alternative modality's results, comparing key echocardiographic parameters.
Main Results:
- Pocket mobile echocardiography demonstrated high sensitivity (e.g., 97% for aortic stenosis) and specificity (e.g., 100% for mitral regurgitation).
- Equivalence testing showed pocket mobile echocardiography outcomes were statistically equivalent to transthoracic echocardiography (P = 7.22 × 10(-7)).
- No significant differences in image quality were observed between the two methods.
Conclusions:
- Rapid bedside pocket mobile echocardiography performed by experienced fellows is comparable to formal transthoracic echocardiography.
- This approach may enable physicians to perform and interpret echocardiograms at the bedside.
- It has the potential to decrease the volume and cost of formal echocardiography studies for hospitalized patients.
Background:
Frequently, hospitalized patients are referred for transthoracic echocardiograms. The availability of a pocket mobile echocardiography device that can be incorporated on bedside rounds by cardiologists may be a useful and frugal alternative.
Methods:
This was a cross-sectional study designed to compare the accuracy of pocket mobile echocardiography images with those acquired by transthoracic echocardiography in a sample of hospitalized patients. Each patient referred for echocardiography underwent pocket mobile echocardiography acquisition and interpretation by a senior cardiology fellow with level II training in echocardiography. Subsequently, transthoracic echocardiography was performed by skilled ultrasonographers and interpreted by experienced echocardiographers. Both groups were blinded to the results of the alternative imaging modality. Visualizability and accuracy for all key echocardiographic parameters (ejection fraction, wall motion abnormalities, left ventricular end-diastolic dimension, inferior vena cava size, aortic and mitral valve pathology, and pericardial effusion) were determined and compared between imaging modalities.
Results:
A total of 240 hospitalized patients underwent echocardiography with pocket mobile echocardiography and transthoracic echocardiography. The mean age was 71 ± 17 years. Pocket mobile echocardiography imaging time was 6.3 ± 1.5 minutes. Sensitivity of pocket mobile echocardiography varied by parameter and was highest for aortic stenosis (97%) and lowest for aortic insufficiency (76%). Specificity also varied by parameter and was highest for mitral regurgitation (100%) and lowest for left ventricular ejection fraction (92%). Equivalence testing revealed the pocket mobile echocardiography outcomes to be significantly equivalent to the transthoracic echocardiography outcomes with no discernible differences in image quality between pocket mobile echocardiography and transthoracic echocardiography (P = 7.22 × 10(-7)). All outcomes remain significant after correcting for multiple testing using the false discovery rate.
Conclusions:
The results from rapid bedside pocket mobile echocardiography examinations performed by experienced cardiology fellows compared favorably with those from formal transthoracic echocardiography studies. For hospitalized patients, this finding could shift the burden of performing and interpreting the echocardiogram to the examining physician and reduce the number and cost associated with formal echocardiography studies.
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