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Individualized medicine from prewomb to tomb
1The Scripps Translational Science Institute, The Scripps Research Institute and Scripps Health, La Jolla, CA 92037, USA.
Cell
|April 1, 2014
Summary
Every individual is biologically unique, even identical twins. Comprehensive
Area of Science:
- Genomics and Personalized Medicine
Background:
- Biological uniqueness is often underestimated, even in identical twins.
- Advances in omics technologies allow for detailed individual biological profiling.
Purpose of the Study:
- To highlight the profound biological uniqueness of each individual.
- To emphasize the potential of comprehensive omics data in healthcare.
Main Methods:
- Comprehensive omics assessment, including DNA/RNA sequencing.
- Characterization of proteome, metabolome, microbiome, autoantibodies, and epigenome.
Main Results:
- Demonstrated that each person possesses one-of-a-kind biological content.
- Confirmed significant individual variation beyond traditional markers like fingerprints.
Conclusions:
- Individualized biological data offer unprecedented opportunities for medical treatment.
- Personalized data can drive the development of novel preventive health strategies.
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