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Updated: May 1, 2026

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
Published on: April 4, 2025
New hydronephrosis and/or vesicoureteral reflux after bladder outlet surgery without augmentation in 75 children with
W Snodgrass1, C Villanueva2, P Gargollo1
1UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9142, USA.
Objective:
We report new upper tract changes in children after bladder neck (BN) surgery without augmentation for neurogenic incontinence.
Materials And Methods:
Consecutive children with neurogenic sphincteric incompetency had BN surgery without augmentation. Postoperative renal sonography and fluoroscopic urodynamics were done at 6 months, 12 months, and then annually.
Results:
There were 75 patients with mean follow-up of 48 months. Of these, 17 (23%) developed new hydronephrosis (HN) or vesicoureteral reflux (VUR). All HN resolved with medical management, as did 25% of VUR cases. Persistent VUR was treated by dextranomer/hyaluronic acid injection, or re-implantation in two patients undergoing re-operative BN surgery. There was no association between these upper tract changes and end filling pressures (<40 cm vs. >40 cm) or continence status (dry vs. wet).
Conclusions:
Upper tract changes developed in 25% of patients with neurogenic bladders after BN surgery without augmentation during a follow-up of 48 months. All new HN and most new VUR resolved with medical management or minimally invasive intervention. No patient developed upper tract changes requiring augmentation.
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