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Related Concept Videos

Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

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Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
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Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
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Depressive Disorders: MDD and Dysthymia01:27

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Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
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Depression: Overview01:18

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Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
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Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

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Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
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Long-term Depression01:03

Long-term Depression

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Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
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Long-term Depression01:05

Long-term Depression

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Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
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Related Experiment Video

Updated: May 1, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

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[Postpartum depression: correlations and predictive factors].

D Amaru, O Le Bon

    Revue Medicale De Bruxelles
    |April 2, 2014
    PubMed
    Summary

    Post-partum depression (PPD) affects new mothers and can lead to psychosis. Key risk factors include relationship status, pregnancy issues, feeling neglected, and self-doubt about maternal roles.

    Area of Science:

    • Psychiatry
    • Perinatal Mental Health
    • Obstetrics

    Context:

    • Post-partum depression (PPD) is a significant mental health concern following childbirth.
    • Early detection is crucial to prevent severe consequences for mother, infant, and family.
    • PPD can escalate to post-partum psychosis, a psychiatric emergency.

    Purpose:

    • To identify psychological and historical factors differentiating women at risk for PPD.
    • To analyze data from 88 women using the Edinburgh Postnatal Depression Scale (EPDS) and personal interviews.
    • To compare women with EPDS scores predictive of PPD against a control group.

    Summary:

    • A study of 88 women found 27.3% had EPDS scores indicating PPD risk, higher than typical rates.
    • Key risk factors identified: cohabitation with a partner, pregnancy-related physical or mental health issues, perceived environmental neglect, and self-deprecating attitudes regarding maternal function.

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    Last Updated: May 1, 2026

    Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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    Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
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  • These indicators are readily identifiable with increased attention to mothers post-delivery.

    • Impact:

    • Highlights the prevalence of PPD risk factors in a studied cohort.
    • Suggests that focused attention on new mothers can facilitate early detection of PPD.
    • Emphasizes the importance of considering psychological and social factors in perinatal care.