Multiple pregnancies following assisted reproductive technologies--a happy consequence or double trouble?

Area of Science:

• Reproductive Medicine
• Obstetrics
• Perinatology

Background:

• Assisted reproduction technologies (ART) are linked to a high incidence of multiple pregnancies (24%).
• Multiple pregnancies elevate risks for maternal and perinatal complications and increase healthcare costs.
• Existing literature on ART twin obstetric outcomes requires comprehensive review.

Purpose of the Study:

• To review and compare obstetric outcomes of twins conceived via ART versus natural conception.
• To discuss methods for mitigating the risk of multiple births in ART.
• To provide evidence-based insights for clinical practice and patient counseling.

Main Methods:

• Literature review focusing on comparative obstetric outcomes.
• Analysis of studies comparing ART twins and naturally conceived twins.
• Examination of techniques for reducing multiple gestation rates.

Main Results:

• ART twins exhibit distinct obstetric profiles compared to naturally conceived twins.
• Specific risks and complications associated with ART-related multiple pregnancies are identified.
• The effectiveness of interventions like elective single embryo transfer is evaluated.

Conclusions:

• Understanding ART twin outcomes is crucial for managing high-risk pregnancies.
• Strategies to reduce multiple births are essential for improving ART safety and efficiency.
• Further research is needed to optimize ART protocols and minimize associated risks.