Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cholecystitis01:20

Cholecystitis

29
Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
29
Gallbladder01:17

Gallbladder

3.2K
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
3.2K
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

2.1K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
2.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advancing rainwater treatment technologies for irrigation of urban agriculture: A pathway toward innovation.

The Science of the total environment·2024
Same author

Berberine Mediates the Production of Butyrate to Ameliorate Cerebral Ischemia via the Gut Microbiota in Mice.

Nutrients·2024
Same author

Proteomic profiling of aqueous humor-derived exosomes in Vogt-Koyanagi-Harada disease and Behcet's uveitis.

Clinical immunology (Orlando, Fla.)·2024
Same author

Novel approach for enhancing skin allograft survival by bioadhesive nanoparticles loaded with rapamycin.

International journal of pharmaceutics·2023
Same author

The Contribution of DNA Ligase 4 Polymorphisms to Colorectal Cancer.

In vivo (Athens, Greece)·2023
Same author

Distribution pattern of dissolved organic matter in pore water of sediments from three typical areas of western Lake Taihu and its environmental implications.

Water science and technology : a journal of the International Association on Water Pollution Research·2023

Related Experiment Video

Updated: May 1, 2026

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb
04:50

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

Published on: January 17, 2025

995

Aspects on gallbladder cancer in 2014.

Ake Åndrén-Sandberg1, Yang Deng

  • 1aDepartment of Surgery, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden bDepartment of Surgery, Ruijin Hospital, Medical School of Shanghai Jiaotong University, Shanghai, People's Republic of China.

Current Opinion in Gastroenterology
|April 2, 2014
PubMed
Summary

Simple cholecystectomy is adequate for early gallbladder cancer (T1a). For T2 lesions, lymph node excision and radical resection improve survival, but extensive surgery may be avoided with negative margins. Management must be stage-based.

More Related Videos

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
04:41

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

1.9K

Related Experiment Videos

Last Updated: May 1, 2026

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb
04:50

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

Published on: January 17, 2025

995
Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
04:41

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

1.9K

Area of Science:

  • Oncology
  • Surgical Oncology
  • Gastroenterology

Background:

  • Gallbladder cancer (GBC) incidence and mortality have declined independently of laparoscopic surgery.
  • Gallbladder carcinoma is found in 3-4% of autopsies and cholelithiasis cases.
  • Genetic alterations in GBC support distinct tumor development pathways, some linked to risk factors.

Purpose of the Study:

  • To review critical aspects of gallbladder cancer (GBC) management.
  • To emphasize the importance of staging in GBC treatment and outcome comparisons.

Main Methods:

  • Review of existing literature on gallbladder cancer management.
  • Analysis of genetic alterations and their association with risk factors.
  • Evaluation of treatment outcomes based on tumor stage.

Main Results:

  • Simple cholecystectomy is sufficient for T1a GBC.
  • Lymph node excision enhances survival for T2 GBC.
  • Radical resection of T2 tumors improves long-term survival compared to standard cholecystectomy.
  • Aggressive surgical approaches are safe with improved techniques.

Conclusions:

  • T1a GBC requires simple cholecystectomy.
  • T2 GBC management benefits from lymph node excision and radical resection, with potential to avoid extensive surgery if margins are clear.
  • Staging is crucial for effective GBC management and comparative analysis.