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The Contribution of DNA Ligase 4 Polymorphisms to Colorectal Cancer.

Yang Deng1,2,3, Tao-Wei Ke4,5, Te-Cheng Yueh5,6,7

  • 1Department of General Surgery, Wuxi Branch of Shanghai Ruijin Hospital, Wuxi, P.R. China.

In Vivo (Athens, Greece)
|December 26, 2023
PubMed
Summary

This study investigated DNA ligase 4 (Lig4) genotypes and colorectal cancer (CRC) risk in Taiwan. No significant association was found between Lig4 rs1805388 genotypes and CRC susceptibility, suggesting it may not be a predictive marker.

Keywords:
Colorectal cancerDNA ligase 4genotypesnon-homologous end-joiningsingle nucleotide polymorphism

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