Related Experiment Video
Updated: May 1, 2026

04:53
Detection of Total Reactive Oxygen Species in Adherent Cells by 2',7'-Dichlorodihydrofluorescein Diacetate Staining
Published on: June 23, 2020
31.9K
A ratiometric fluorescent probe for the detection of hydroxyl radicals in living cells
Luyan Meng1, Yongquan Wu, Tao Yi
1Department of Chemistry & Innovation Center of Chemistry for Energy Materials, Fudan University, 220 Handan Road, Shanghai 200433, P. R. China. yitao@fudan.edu.cn.
Abstract:
A naphthalimide-naphthyridine derivative has been synthesized for the detection of hydroxyl radicals. It can distinguish hydroxyl radicals from other reactive oxygen species with high selectivity and short response time. Moreover, it has no cellular toxicity, and can be effectively used for intracellular detection of hydroxyl radicals.

