Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interferons in cell growth and development.

G Romeo, G Fiorucci, G B Rossi

    Trends in Genetics : TIG
    |January 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Comprehensive analysis of β- and γ-human papillomaviruses in actinic keratosis and apparently healthy skin of elderly patients.

    The British journal of dermatology·2019
    Same author

    Role of interferons in cell differentiation and development.

    Cytotechnology·2012
    Same author

    Cancer regulator microRNA: potential relevance in diagnosis, prognosis and treatment of cancer.

    Current medicinal chemistry·2011
    Same author

    Senescence and cell death pathways and their role in cancer therapeutic outcome.

    Current medicinal chemistry·2009
    Same author

    Perspectives in biomolecular therapeutic intervention in cancer: from the early to the new strategies with type I interferons.

    Current medicinal chemistry·2007
    Same author

    TNF-related apoptosis-inducing ligand (TRAIL) as a pro-apoptotic signal transducer with cancer therapeutic potential.

    Current pharmaceutical design·2005
    Same journal

    Genetic suppressors as new therapeutic targets for Mendelian diseases.

    Trends in genetics : TIG·2026
    Same journal

    Beyond housekeeping: snRNA diversity, regulation, and human disease.

    Trends in genetics : TIG·2026
    Same journal

    Rethinking mitochondrial metabolism: Intraindividual variability meets population constraints.

    Trends in genetics : TIG·2026
    Same journal

    A role for epigenetics in rapid adaptation.

    Trends in genetics : TIG·2026
    Same journal

    The myth of asexual fungi.

    Trends in genetics : TIG·2026
    Same journal

    Rethinking molecular evolution through protein language model embeddings.

    Trends in genetics : TIG·2026
    See all related articles

    Interferons (IFNs) regulate cell growth and differentiation. Research is identifying specific IFN-inducible proteins that mediate these crucial biological effects.

    Area of Science:

    • Immunology
    • Molecular Biology
    • Cell Biology

    Background:

    • Interferons (IFNs) are known for inducing antiviral states in cells.
    • Beyond antiviral functions, IFNs act as natural regulators of fundamental cellular processes.
    • These processes include cell growth, differentiation, and development.

    Purpose of the Study:

    • To explore the regulatory roles of interferons (IFNs) in cellular physiology.
    • To investigate the impact of IFNs on cell growth, differentiation, and development.
    • To understand the mechanisms by which IFNs modulate oncogene expression.

    Main Methods:

    • Analysis of interferon-inducible proteins.
    • Investigating the up- or down-regulation of oncogenes by IFNs.
    • Review of existing literature on IFN functions and molecular mediators.

    Related Experiment Videos

    Main Results:

    • Interferons (IFNs) are confirmed as key regulators of cell growth and differentiation.
    • IFN-mediated regulation of oncogenes is a potential mechanism affecting cell physiology.
    • The repertoire of IFN-inducible proteins is expanding, suggesting diverse biological roles.

    Conclusions:

    • Interferons (IFNs) possess significant regulatory functions extending beyond antiviral activity.
    • Further research is necessary to pinpoint the specific IFN-inducible proteins mediating these diverse cellular effects.
    • Understanding these mediators is crucial for elucidating the full spectrum of IFN biological actions.