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Updated: May 1, 2026

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Published on: May 10, 2021

Second-opinion pathologic review is a patient safety mechanism that helps reduce error and decrease waste.

Lavinia P Middleton¹, Thomas W Feeley², Heidi W Albright²

¹University of Texas MD Anderson Cancer Center, Houston, TX lpmiddleton@mdanderson.org.

Journal of Oncology Practice

|April 4, 2014

Summary

This summary is machine-generated.

Subspecialty pathologic review of cancer patients before treatment revealed significant diagnostic discrepancies. This second review improves cancer care by ensuring accurate diagnoses and evidence-based treatment plans.

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Last Updated: May 1, 2026

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Published on: May 10, 2021

Area of Science:

Oncology
Pathology
Health Services Research

Background:

Healthcare delivery faces challenges with rising costs and variable quality.
Value-based healthcare delivery is increasingly recognized for cost control and quality improvement.
Subspecialty pathologic review before cancer therapy is a proven method to enhance care.

Purpose of the Study:

To examine the diagnostic error rate in cancer patients at a tertiary care hospital.
To demonstrate the value of subspecialty pathologic review prior to treatment initiation.

Main Methods:

A one-month review (September 2011) of all pathology cases for clinical consultation.
Pathology specimens were reviewed by subspecialty-expert pathologists.
Data were correlated within a pathology database.

Main Results:

2,718 patient cases were reviewed.
Pathology report discrepancies occurred in 25% of cases.
Major discrepancies affecting patient care were found in 6.2% of cases (169 reports).

Conclusions:

Subspecialty pathologist review of outside pathology improves cancer care.
Multidisciplinary cancer care is enhanced by expert second reviews.
Accurate diagnoses from second reviews lead to evidence-based treatment plans and better clinical outcomes.