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Related Experiment Video

Updated: Jan 2, 2026

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
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Atrial Fibrillation and Stroke Risk in Patients With Cancer: A Primer for Oncologists.

Marc Sorigue1, Milos D Miljkovic2

  • 1ICO-Hospital Germans Trias i Pujol.IJC, UAB, Badalona, Spain.

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|December 12, 2019
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Managing anticoagulation for cancer patients with atrial fibrillation (AF) is complex due to higher bleeding risks. Evidence suggests individualized treatment based on bleeding risk, with a need for more high-quality research.

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Area of Science:

  • Cardiology
  • Oncology
  • Pharmacology

Background:

  • Atrial fibrillation (AF) and cancer are prevalent conditions.
  • Limited data exists on anticoagulation management and cerebrovascular outcomes for patients with both conditions.

Purpose of the Study:

  • To review stroke risk and AF management in cancer patients.
  • To provide a decision algorithm and practical recommendations for anticoagulation.

Main Methods:

  • Review of relevant studies on stroke risk and AF management in cancer patients.
  • Development of a decision algorithm based on available evidence.
  • Discussion of limitations in current evidence.

Main Results:

  • Cancer patients with AF have similar stroke risk but higher bleeding risk compared to the general population.
  • Anticoagulation decisions are complex due to increased bleeding risk.
  • Low-quality evidence suggests stopping anticoagulation in high bleeding risk patients.

Conclusions:

  • Anticoagulation decisions for cancer patients with AF require careful consideration of bleeding risk.
  • Individualized treatment strategies are recommended.
  • High-quality evidence is needed to guide anticoagulation in this patient population.