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Updated: May 1, 2026
05:46
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
1.8K
Congenital uveal malignant melanoma
Parnchat Pukrushpan1, Wasee Tulvatana1, Rosana Pittayapongpat2
1Chulalongkorn University, Bangkok, Thailand.
Summary
This study details a rare congenital uveal melanoma case in an infant. Pathological findings confirmed malignant melanoma with extraocular extension, necessitating aggressive treatment.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Pathology
Background:
- Congenital uveal melanoma is an exceedingly rare ocular malignancy in infants.
- Early detection and diagnosis are crucial for managing intraocular tumors in neonates.
Observation:
- A 7-week-old infant presented with a congenital pigmented lesion near the cornea.
- Clinical examination revealed an enlarged globe, iris mass, and shallow anterior chamber.
- Magnetic resonance imaging confirmed an intraocular mass.
Findings:
- Pathological examination confirmed epithelioid cell type malignant melanoma.
- The tumor exhibited extraocular extension.
- The infant underwent enucleation, chemotherapy, and subtotal exenteration.
Implications:
- This case highlights the importance of recognizing rare congenital eye tumors.
- Aggressive multimodal treatment may be required for advanced congenital uveal melanoma.
- Further research into the etiology and optimal management of these rare tumors is warranted.
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