Related Experiment Video
Updated: May 1, 2026

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
Published on: March 1, 2024
Scoring nail psoriasis.
Karlijn M G Klaassen1, Peter C M van de Kerkhof1, Maarten T Bastiaens2
1Department of Dermatology, Radboud university medical center, Nijmegen, The Netherlands.
A new scoring system, the Nijmegen-Nail psoriasis Activity Index tool (N-NAIL), effectively assesses nail psoriasis severity. It demonstrated superior correlation and reliability compared to existing methods, offering a promising tool for future treatment studies.
Area of Science:
- Dermatology
- Clinical Assessment
- Medical Informatics
Background:
- Scoring systems are crucial for evaluating disease severity and treatment efficacy in medical practice.
- Nail psoriasis significantly impacts patients' quality of life, necessitating accurate assessment tools.
Purpose of the Study:
- To evaluate the performance of existing nail psoriasis severity scoring systems.
- To develop and validate a novel, reliable scoring system for nail psoriasis.
Main Methods:
- A prospective, observational study involving 36 patients diagnosed with fingernail psoriasis.
- Evaluation of seven scoring systems including NAPSI, Psoriasis Nail Severity Score, Baran, and the newly developed N-NAIL.
- Correlation with Physician Global Assessment and assessment of interrater and intrarater reliability for N-NAIL.
Main Results:
- The N-NAIL showed the highest correlation (r = 0.861, P < .01) with Physician Global Assessment.
- The Baran system and Psoriasis Nail Severity Score also demonstrated acceptable correlations (r ≈ 0.735, P < .01).
- N-NAIL exhibited excellent intrarater and interrater reliability.
Conclusions:
- The N-NAIL is a highly reliable and accurate tool for assessing nail psoriasis clinical severity.
- Existing systems like Baran and Psoriasis Nail Severity Score show moderate utility.
- A robust scoring system is essential given the anticipated advancements in nail psoriasis treatment research.
Related Concept Videos
Accessory Structures of the Skin: Nails
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
Peripheral Artery Disease IV: Nursing Management
Diabetic Foot Ulcer
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Nephrotic Syndrome II : Assessment and Medical Management

