Related Experiment Video

Updated: May 1, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

19.1K

Headaches and vasculitis

David S Younger1

  • 1Department of Neurology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA; Division of Neurology, Department of Medicine, Lenox Hill Hospital, 100 East 77th Street, New York, NY 10021, USA.

Neurologic Clinics
|April 8, 2014
PubMed

Insights

Vasculitis involves blood vessel inflammation, potentially affecting the central nervous system (CNS). Early diagnosis and treatment are crucial to prevent brain damage from CNS vasculitis.

Area of Science:

  • Neurology
  • Immunology
  • Rheumatology

Background:

  • Vasculitis encompasses diverse disorders characterized by blood vessel inflammation and tissue damage.
  • Headaches can indicate central nervous system (CNS) vasculitis.
  • CNS vasculitis can be primary (intracranial vessels only) or secondary to systemic conditions.

Purpose of the Study:

  • To highlight the significance of headache as an early indicator of central nervous system vasculitis.
  • To differentiate between primary and secondary CNS vasculitis.
  • To emphasize the need for prompt diagnosis and management of suspected vasculitis.

Main Methods:

  • Review of clinical presentations and diagnostic criteria for vasculitis.
  • Analysis of the role of headache in identifying CNS vasculitis.
  • Discussion of primary versus secondary CNS vasculitis classifications.

Main Results:

  • Headache is a key symptom suggesting potential CNS vasculitis.
  • Central nervous system vasculitis requires careful differentiation between primary and secondary forms.
  • Prompt evaluation is essential for suspected cases.

Conclusions:

  • Early recognition of CNS vasculitis, often signaled by headache, is critical.
  • Distinguishing primary from secondary CNS vasculitis guides appropriate treatment.
  • Timely intervention can prevent severe neurological complications like cerebral ischemia or infarction.

Keywords:
Central nervous systemHeadachesIntracranial vesselsVasculitis

More Related Videos

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

6.8K
Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache05:40

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

8.6K

Related Concept Videos

Acute Inflammation II: Local and Systemic Effects01:25

Acute Inflammation II: Local and Systemic Effects

Acute inflammation produces a coordinated set of local and systemic changes that limit injury, eliminate pathogens, and initiate repair. These responses arise within minutes of infection, trauma, or chemical insult and are driven by vascular alterations and leukocyte-derived mediators. When the stimulus resolves, the reaction typically abates within days.Local EffectsAt the site of injury, arteriolar vasodilation increases blood flow, resulting in redness and warmth. Simultaneously, increased...
56
Veins of Head and Neck01:19

Veins of Head and Neck

The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
7.7K
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
30
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
15
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this...
19
Arteries of the Head and Neck01:26

Arteries of the Head and Neck

The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
4.3K