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iChip

iChip

The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...

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Updated: May 1, 2026

Microfabrication of Chip-sized Scaffolds for Three-dimensional Cell cultivation

Microfabrication of Chip-sized Scaffolds for Three-dimensional Cell cultivation

Published on: May 12, 2008

Building a Fab on a Chip.

Matthias Imboden¹, Han Han, Thomas Stark

¹Department of Electrical and Computer Engineering, Boston University, Boston, Massachusetts 02215, USA. mimboden@bu.edu.

|April 8, 2014

Summary

This summary is machine-generated.

Researchers explored integrating semiconductor fabrication plant (fab) functions onto a single silicon chip. This "Fab on a Chip" approach offers significant cost savings for nanometer-scale device manufacturing.

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Last Updated: May 1, 2026

Microfabrication of Chip-sized Scaffolds for Three-dimensional Cell cultivation

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Published on: May 12, 2008

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

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Published on: October 20, 2018

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Area of Science:

Materials Science
Electrical Engineering
Nanotechnology

Background:

Semiconductor fabrication plants (fabs) are highly complex industrial facilities with substantial costs, often nearing $10 billion.
Current manufacturing processes involve large-scale, specialized machinery for device production.

Purpose of the Study:

To investigate the feasibility of consolidating the entire functionality of a semiconductor fab onto a single silicon chip.
To explore potential cost reductions in device manufacturing through a miniaturized, integrated approach.

Main Methods:

Development of micro-scale versions of macro-scale fabrication machinery.
Integration of all necessary components onto a single silicon chip.
Focus on applications, particularly at the nanometer scale.

Main Results:

Demonstration of a viable technological path towards a 'Fab on a Chip'.
Identification of significant cost-saving potential for specific applications.
Integration of micro-fabricated components to replicate macro-fab functions.

Conclusions:

The technology currently exists to realize a 'Fab on a Chip' concept.
This integrated chip-level fabrication offers a paradigm shift for nanometer-scale device production.
The approach promises substantial economic benefits and streamlined manufacturing processes.