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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
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Ambient Temperature and Obesity.

Douglas R Moellering1, Daniel L Smith2

  • 1Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA ; Diabetes Research and Training Center, University of Alabama at Birmingham, Birmingham, AL, USA.

Current Obesity Reports
|April 8, 2014
PubMed
Summary
This summary is machine-generated.

Modern humans avoid cold, minimizing energy expenditure and potentially increasing obesity risk. Ambient temperature significantly impacts energy intake and expenditure, warranting further study for obesity susceptibility.

Keywords:
Ambient TemperatureBrown Adipose TissueDietEnergy ExpenditureObesityThermogenesisThermoneutral

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Area of Science:

  • Physiology
  • Metabolic Health
  • Environmental Science

Background:

  • Homeotherms regulate body temperature, typically above ambient levels.
  • Decreased ambient temperatures necessitate increased energy expenditure for thermal homeostasis.
  • Modern climate control insulates humans from temperature extremes, minimizing energy demands.

Purpose of the Study:

  • To investigate the role of ambient temperature in energy balance.
  • To explore the link between reduced environmental temperature exposure and rising obesity rates.
  • To examine metabolic and physiological responses to temperature in lean versus obese individuals.

Main Methods:

  • Review of studies on animal and human exposure to varying ambient temperatures.
  • Analysis of energy intake and expenditure data in relation to environmental temperature.
  • Comparison of metabolic and physiological responses between obese and lean subjects.

Main Results:

  • Ambient temperature is a significant factor influencing both energy intake and expenditure.
  • Reduced exposure to cooler temperatures may reduce overall energy demands.
  • Obese and lean individuals may exhibit different metabolic responses to ambient temperature.

Conclusions:

  • Ambient temperature is a critical, yet under-explored, factor in energy balance.
  • Minimizing exposure to thermal challenges may contribute to obesity susceptibility.
  • Further research into ambient temperature's role in obesity is warranted.