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Obstacles and opportunities in Alzheimer's clinical trial recruitment
Abstract:
The 2012 National Plan to Address Alzheimer's Disease set an ambitious goal: to both prevent and effectively treat Alzheimer's disease by 2025. To reach this goal, tens of thousands of volunteers will be needed to participate in clinical trials to test promising new interventions and therapies. To mobilize these volunteers and their health care providers to participate in future clinical trials, it will be necessary to achieve a better understanding of the barriers keeping people from participating in Alzheimer's research; form innovative partnerships among researchers, health care and social service providers, and the public; and develop more-effective outreach strategies. In this article we explore recruitment issues, including those unique to Alzheimer's studies, and we suggest concrete steps such as establishing a structured consortium linking all of the registries of Alzheimer's trials and establishing new partnerships with community and local organizations that can build trust and understanding among patients, caregivers, and providers.
Insights
Recruiting volunteers for Alzheimer's disease clinical trials is crucial. Understanding barriers and forming community partnerships are key to increasing participation in Alzheimer's research.
Area of Science:
- Neuroscience
- Clinical Research
- Public Health
Background:
- The 2012 National Plan to Address Alzheimer's Disease aims for prevention and effective treatment by 2025.
- Achieving this goal necessitates a significant increase in clinical trial participation.
Purpose of the Study:
- To explore barriers to Alzheimer's disease clinical trial recruitment.
- To propose strategies for enhancing volunteer and healthcare provider engagement in Alzheimer's research.
Main Methods:
- Analysis of recruitment challenges specific to Alzheimer's studies.
- Identification of potential solutions including consortiums and community partnerships.
Main Results:
- Understanding recruitment barriers is essential for mobilizing volunteers.
- Innovative partnerships and effective outreach are vital for success.
Conclusions:
- Establishing a linked registry consortium can streamline recruitment.
- Collaborating with community organizations can build trust and increase participation in Alzheimer's clinical trials.
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