Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Burn Injuries01:22

Burn Injuries

4.4K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
4.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Magnitude and predictors of psychological burden of care among informal caregivers of Noma survivors.

Journal of stomatology, oral and maxillofacial surgery·2026
Same author

Comparison of the Ivermectin and Lopinavir/Ritonavir Treatment Outcomes among COVID-19 Mild to Moderate Cases in Kaduna State.

West African journal of medicine·2022
Same author

Stochastic models in seed dispersals: random walks and birth-death processes.

Journal of biological dynamics·2019
Same author

The impact of operative time and hypothermia in acute burn surgery.

Burns : journal of the International Society for Burn Injuries·2017
Same author

Dynamic and morphologic evaluation of erectile dysfunction on penile doppler sonography and contrast cavernosography.

Nigerian journal of clinical practice·2017
Same author

The effect of obesity on adverse outcomes and metabolism in pediatric burn patients.

International journal of obesity (2005)·2011
Same journal

The BmCPV-derived viral small peptide vsp1S4(-) suppresses viral replication by triggering apoptosis via the ROS-JNK signalling pathway.

Cellular and molecular life sciences : CMLS·2026
Same journal

UBE2L6 promotes invasion and metastasis of triple-negative breast cancer by enhancing autophagy through STK38 ISGylation.

Cellular and molecular life sciences : CMLS·2026
Same journal

Inhibition of ferroptosis via SLC25A39-NRF2 axis drives Osimertinib resistance in lung adenocarcinoma.

Cellular and molecular life sciences : CMLS·2026
Same journal

PHLDA1 knockdown exacerbates emphysema in COPD by attenuating proliferation of alveolar type II cells via modulating GLI1 nuclear translocation.

Cellular and molecular life sciences : CMLS·2026
Same journal

Single-Cell dissection of fibrodysplasia ossificans progressiva identifies SPP1 as a mediator of macrophage-fibroadipogenic progenitors crosstalk.

Cellular and molecular life sciences : CMLS·2026
Same journal

Ablation of the renal tubular gluconeogenic enzyme PCK1 drives AKI-to-CKD transition by negatively regulating the TGF-β/Smad3 signaling pathway.

Cellular and molecular life sciences : CMLS·2026
See all related articles

Related Experiment Video

Updated: May 1, 2026

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device
04:04

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device

Published on: December 27, 2024

1.9K

Animal models in burn research.

A Abdullahi1, S Amini-Nik, M G Jeschke

  • 1Division of Plastic Surgery, Department of Surgery, University of Toronto, Toronto, Canada, abdikarim.abdullahi@sunnybrook.ca.

Cellular and Molecular Life Sciences : CMLS
|April 10, 2014
PubMed
Summary
This summary is machine-generated.

This review evaluates animal models for burn injury research, focusing on skin healing in mice, rats, and pigs. Understanding model limitations is crucial for developing clinically relevant burn treatments.

More Related Videos

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
08:40

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

Published on: August 23, 2022

6.2K
Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
02:49

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes

Published on: February 23, 2024

2.4K

Related Experiment Videos

Last Updated: May 1, 2026

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device
04:04

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device

Published on: December 27, 2024

1.9K
Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
08:40

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

Published on: August 23, 2022

6.2K
Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
02:49

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes

Published on: February 23, 2024

2.4K

Area of Science:

  • Biomedical Engineering
  • Translational Medicine
  • Trauma Research

Background:

  • Burn injury is a complex trauma affecting millions annually, causing multi-organ deficits.
  • In vitro models are insufficient for studying burn pathophysiology due to its systemic nature.
  • Animal models are essential for understanding burn injury and testing treatments.

Purpose of the Study:

  • To review common animal models for burn injury research.
  • To elucidate the advantages and limitations of these models for translational applications.
  • To guide researchers in selecting appropriate models for burn research.

Main Methods:

  • Focus on skin healing models in mice, rats, and pigs.
  • Briefly discuss models for hypermetabolic burn characteristics.
  • Analyze economic costs associated with different animal models.

Main Results:

  • Mouse, rat, and pig models offer distinct advantages for studying burn-related skin healing.
  • Specific models exist to investigate hypermetabolic states post-burn.
  • Economic factors vary significantly between models, influencing research feasibility.

Conclusions:

  • Selection of an appropriate animal model is critical for the success of burn research.
  • Understanding model-specific benefits and drawbacks enhances translational relevance.
  • Cost-effectiveness should be considered alongside scientific rigor when choosing a burn model.