Related Experiment Video
Updated: May 1, 2026
![Solid-phase Synthesis of [4.4] Spirocyclic Oximes](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F58508.jpg&w=3840&q=50)
Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
Rhodium-catalyzed tandem cyclization/Si-C activation reaction for the synthesis of siloles
Qing-Wei Zhang1, Kun An, Wei He
1School of Medicine and Tsinghua-Peking Joint Centers for Life Science, Tsinghua University, Beijing 100084 (China).
Abstract:
Siloles represent an important emerging class of photoluminescent materials. Reported herein is a new synthetic strategy involving a tandem cyclization/Si-C activation reaction featuring high efficiency, wide substrate scope, and practical utility. This method enabled the first synthesis of benzofuran siloles as well as rapid access to conjugated siloles. During the course of the study we also uncovered an unusual yet general Si-C(sp(2)) activation in the presence of π acids.
More Related Videos
12:27Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes
Published on: September 8, 2013
10:17Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
Related Concept Videos
Cycloaddition Reactions: Overview
Preparation and Reactions of Sulfides
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide
Diels–Alder Reaction Forming Cyclic Products: Stereochemistry
Alkenes via Reductive Coupling of Aldehydes or Ketones: McMurry Reaction
Cyclohexenones via Michael Addition and Aldol Condensation: The Robinson Annulation