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Related Concept Videos

Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

33
Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory...
33
Diabetic Retinopathy01:27

Diabetic Retinopathy

55
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
55
Complications of Diabetes Mellitus01:22

Complications of Diabetes Mellitus

35
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...
35
Diabetic Neuropathy01:22

Diabetic Neuropathy

59
DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
59
Diabetic Nephropathy01:28

Diabetic Nephropathy

32
Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration...
32
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

702
 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
702

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Related Experiment Video

Updated: May 1, 2026

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
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Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers

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[An update on diabetic foot].

Gabriel Seguel

    Revista Medica De Chile
    |April 11, 2014
    PubMed
    Summary
    This summary is machine-generated.

    Diabetic foot complications lead to 70% of adult amputations, significantly impacting patients and healthcare resources. This review updates knowledge on diabetic foot management to reduce amputations and improve patient quality of life.

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    Evaluating the Function of the Foot Core System in the Elderly
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    Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
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    Evaluating the Function of the Foot Core System in the Elderly
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    Evaluating the Function of the Foot Core System in the Elderly

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    Area of Science:

    • Endocrinology and Metabolic Diseases
    • Vascular Surgery
    • Public Health

    Context:

    • Diabetic foot is a major cause of adult amputations, accounting for 70% and imposing a significant burden on healthcare systems.
    • Recent national health surveys show a substantial percentage of diabetic patients seeking care for foot complications.
    • Rising global and national diabetes prevalence and increased life expectancy necessitate public health system adaptation to diabetic foot care.

    Purpose:

    • To provide an updated review of current knowledge regarding diabetic foot complications.
    • To highlight the need for adopting and implementing evidence-based interventions for diabetic foot management.
    • To address the deficiency in experience with effective diabetic foot interventions within the country.

    Summary:

    • Diabetic foot complications are a leading cause of lower-extremity amputations in adults.
    • Effective interventions, though tested internationally, have limited application locally, contributing to high amputation rates.
    • An update on diabetic foot knowledge is crucial for improving patient outcomes and reducing healthcare costs.

    Impact:

    • Reducing diabetic foot-related amputations can significantly improve patient quality of life.
    • Implementing advanced management strategies can alleviate the strain on healthcare resources.
    • Enhanced understanding and application of diabetic foot care protocols are vital for public health.