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Updated: May 1, 2026

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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
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[Acrodermatitis enteropathica: report of one case].
Summary
Acrodermatitis enteropathica, a rare zinc deficiency disorder, presents with hair loss, diarrhea, and skin sores. Prompt zinc supplementation effectively treats this condition, as demonstrated in a case study.
Area of Science:
- Dermatology
- Nutritional Science
- Internal Medicine
Background:
- Acrodermatitis enteropathica is an uncommon genetic or acquired zinc deficiency disorder.
- The condition classically presents with alopecia, diarrhea, and acral/periorificial dermatitis.
- Zinc supplementation is the established treatment for this condition.
Observation:
- A case report details a 31-year-old indigent female with a history of drug addiction.
- The patient presented with a mucocutaneous syndrome consistent with acrodermatitis enteropathica.
- This presentation occurred in the context of potential nutritional compromise due to socioeconomic and substance abuse factors.
Findings:
- The patient exhibited clinical features strongly indicative of acrodermatitis enteropathica.
- Following zinc supplementation, the patient demonstrated a positive clinical response.
- This suggests zinc deficiency was the underlying cause of her symptoms.
Implications:
- This case highlights the importance of considering acrodermatitis enteropathica in patients with characteristic symptoms, regardless of typical risk factors.
- It underscores the efficacy of zinc supplementation in treating this disorder, even in complex patient populations.
- Early diagnosis and intervention with zinc can significantly improve patient outcomes and prevent long-term complications.
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