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Updated: May 1, 2026

Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat
Published on: November 21, 2025
Complex regional pain syndrome in a 15-year-old girl successfully treated with continuous epidural anesthesia
Yoshiaki Saito1, Shimpei Baba1, Akio Takahashi2
1Department of Child Neurology, National Center of Neurology and Psychiatry (NCNP), Kodaira, Tokyo, Japan.
Abstract:
A 15-year-old girl developed severe pain in her right upper limb within a few days after she experienced an astatic epileptic seizure accompanied by falling on her right side. She was treated with fluid infusion through a cannula into her right hand. Swelling, mild flaring, and muscle weakness of the right arm subsequently appeared. Pharmacotherapy and stellate ganglion block were ineffective, and continuous epidural anesthesia was commenced 14 days after the falling event. The pain and accompanying symptoms completely disappeared within 5 days. Early treatment with continuous epidural anesthesia may be a promising option for the management of complex regional pain syndrome during childhood.
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