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[Locally advanced cardia carcinoma--is resection worthwhile?].
A H Hölscher1, M Schüler, S Thorban
1Chirurgische Klinik und Poliklinik, Technische Universität München.
Deutsche Medizinische Wochenschrift (1946)
|June 30, 1989
Summary
Complete resection (R0) of locally advanced carcinoma of the cardia significantly improves survival. Surgical intervention is beneficial even for advanced tumors when complete tumor removal is achievable.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Oncology
Background:
- Carcinoma of the cardia presents a significant challenge in surgical oncology.
- Prognosis for locally advanced disease is often poor, necessitating evaluation of treatment efficacy.
Purpose of the Study:
- To analyze the long-term outcomes of patients with carcinoma of the cardia.
- To determine the impact of complete tumor resection (R0) on survival in advanced cases.
Main Methods:
- Prospective analysis of 217 patients with carcinoma of the cardia.
- Evaluation of operability, resection rates, and survival based on tumor stage and resection completeness.
Main Results:
- Operability rate was 81%, with a resection rate of 99% among operable patients.
- R0 resection was achieved in 59% of T4 stage patients, showing significantly higher median survival (12.5 months) compared to those with lymph node spread (6.0 months).
- Palliative endoscopic treatment resulted in a median survival of 5 months.
Conclusions:
- Resection of locally advanced carcinoma of the cardia is indicated when R0 resection is feasible.
- Surgical intervention, even for advanced stages, can yield improved survival outcomes if complete tumor removal is achieved.