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Updated: May 1, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
[Aortitis due to Salmonella]
History And Clinical Findings:
A 72-year-old man received treatment with amoxicillin/clavulanic acid because of fever and abdominal pain as an outpatient setting. Salmonella enteritidis infection was confirmed by a positive blood culture. The febrile patient showed abdominal tenderness on palpation.
Investigations:
CT and PET scans revealed an aneurysmatic soft tissue inflammation which was interpreted as infectious aortitis in the context of salmonella bacteraemia.
Treatment And Course:
After several weeks of antibiotic treatment with ceftriaxone, an elective reconstruction using xenopericard with replacement of the mesenterial vessels was performed. After a postoperative course of antibiotics the patient recovered completely.
Conclusion:
In patients with positive blood cultures for Salmonella in combination with fever, back or abdominal pain a workup for infectious aortitis and a rapid treatment is recommended.
Insights
Salmonella bacteraemia can cause infectious aortitis. Prompt diagnosis and treatment, including surgery, are crucial for recovery in patients with Salmonella infection and symptoms like fever and abdominal pain.
Area of Science:
- Infectious Diseases
- Cardiovascular Surgery
- Medical Microbiology
Background:
- Salmonella bacteraemia is a serious infection.
- Infectious aortitis is a rare but life-threatening complication.
Observation:
- A 72-year-old male presented with fever and abdominal pain, diagnosed with Salmonella enteritidis bacteraemia.
- Imaging revealed aneurysmatic soft tissue inflammation, consistent with infectious aortitis.
Findings:
- The patient underwent successful surgical reconstruction of the aorta using xenopericard and mesenterial vessel replacement.
- A combination of antibiotic therapy (amoxicillin/clavulanic acid, ceftriaxone) and surgery led to complete recovery.
Implications:
- Prompt workup for infectious aortitis is recommended for patients with Salmonella bacteraemia and symptoms like fever or abdominal/back pain.
- Multidisciplinary management involving infectious disease specialists and cardiovascular surgeons is vital for favorable outcomes.
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