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Updated: Apr 25, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
[Subacute lower back pain and acute kidney failure in a 47-year old man]
T Tritschler1, J Bleisch, A Al Rifai
1Nephrologie und Dialysezentrum, Klinik für Innere Medizin, Spital Zollikerberg, Zollikerberg, Schweiz.
Abstract:
A 47-year-old man presented with subacute, low back pain and increased creatinine levels. A CT scan showed an extrinsic, bilateral compression of the ureters by a retroperitoneal mass with pronounced uptake of 18F-fluorodeoxyglucose in positron emission tomography. Histological findings were consistent with the diagnosis of retroperitoneal fibrosis. Urological decompression was performed. The initiated corticosteroids led to a rapid clinical improvement and regression of the retroperitoneal mass. A relapse occurred after tapering of corticosteroids with a prompt response to increase of the dosage.
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