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Reservoir of Infection

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...

Cholera

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Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...

Tonsillitis I: Introduction

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.

Bacterial Gastroenteritis

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Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...

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Clinical Significance of Antibiotic Resistance

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Related Experiment Video

Updated: May 1, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

[Aortitis due to Salmonella].

T Stelzer¹, L T Heuss¹, R Schorn¹

¹Medizinische Klinik, Spital Zollikerberg, Schweiz.

Deutsche Medizinische Wochenschrift (1946)

|April 12, 2014

Summary

This summary is machine-generated.

Salmonella bacteraemia can cause infectious aortitis. Prompt diagnosis and treatment, including surgery, are crucial for recovery in patients with Salmonella infection and symptoms like fever and abdominal pain.

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Chronic Salmonella Infected Mouse Model

Chronic Salmonella Infected Mouse Model

Published on: May 31, 2010

Area of Science:

Infectious Diseases
Cardiovascular Surgery
Medical Microbiology

Background:

Salmonella bacteraemia is a serious infection.
Infectious aortitis is a rare but life-threatening complication.

Observation:

A 72-year-old male presented with fever and abdominal pain, diagnosed with Salmonella enteritidis bacteraemia.
Imaging revealed aneurysmatic soft tissue inflammation, consistent with infectious aortitis.

Findings:

The patient underwent successful surgical reconstruction of the aorta using xenopericard and mesenterial vessel replacement.
A combination of antibiotic therapy (amoxicillin/clavulanic acid, ceftriaxone) and surgery led to complete recovery.

Implications:

Prompt workup for infectious aortitis is recommended for patients with Salmonella bacteraemia and symptoms like fever or abdominal/back pain.
Multidisciplinary management involving infectious disease specialists and cardiovascular surgeons is vital for favorable outcomes.