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Related Concept Videos

Membrane Fluidity01:26

Membrane Fluidity

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Membrane fluidity is explained by the fluid mosaic model of the cell membrane, which describes the plasma membrane structure as a mosaic of components—including phospholipids, cholesterol, proteins, and carbohydrates—that gives the membrane a fluid character.
Mosaic nature of the membrane
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Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.
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Cells use energy-requiring bulk transport mechanisms to transfer large particles, or large amounts of small particles, into or out of the cell. The cells envelop the particles in spherical membranes called vesicles or vacuoles. Vesicles that transport material into the cell are built from the cell membrane. These vesicles encapsulate external molecules and transport them into the cell in a process called endocytosis.
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Proof-of-Concept for Gas-Entrapping Membranes Derived from Water-Loving SiO2/Si/SiO2 Wafers for Green Desalination
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Flow over a membrane-covered, fluid-filled cavity.

Scott L Thomson1, Luc Mongeau2, Steven H Frankel2

  • 1Department of Mechanical Engineering, Brigham Young University, Provo, UT, 84602, Ph. 1-801-422-4980.

Computers & Structures
|April 12, 2014
PubMed
Summary
This summary is machine-generated.

Fluid flow over a membrane-covered cavity can cause deformation. High viscosity leads to steady states, while low viscosity and high pressure can cause large vibrations, impacting flow dynamics.

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Area of Science:

  • Fluid dynamics
  • Bioengineering
  • Computational mechanics

Background:

  • Membranes covering fluid cavities are crucial in biological systems, such as vocal folds.
  • Understanding flow-induced vibrations is key to modeling phenomena like voice production.

Purpose of the Study:

  • To investigate the flow-induced response of a membrane covering a fluid-filled cavity.
  • To analyze membrane deformation and cavity flow under various conditions.
  • To explore the model's application in synthetic vocal fold research.

Main Methods:

  • Finite element analysis (FEA) was employed to simulate the system.
  • Parametric studies were conducted varying flow and membrane properties.
  • Asymmetric configurations with differing membrane stiffness were examined.

Main Results:

  • Streamwise transmural pressure gradients drove membrane deformation.
  • High cavity fluid viscosity resulted in steady intracavity pressure and deflection.
  • Low viscosity and high upstream pressure led to large-amplitude membrane vibrations.
  • Asymmetric cavities reduced or stopped vibrations and skewed the downstream flow field.

Conclusions:

  • The study provides insights into flow-structure interactions in membrane-covered cavities.
  • Findings are relevant for developing synthetic models of vocal fold cover layers.
  • Control over vibration amplitude and flow fields can be achieved through asymmetry.