Related Experiment Video
Updated: May 1, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Variability in intraosseous flush practices of emergency physicians.
Joseph S Sontgerath1, Bernard J Rubal2, Robert A DeLorenzo3
1Department of Emergency Medicine, Fort Sam Houston, TX 78234.
Intraosseous (IO) procedures show significant variability in generated pressures among providers, with a 35-fold difference observed. Extending flush duration can help limit peak intraosseous pressure during these critical interventions.
Area of Science:
- Emergency Medicine
- Orthopedic Procedures
- Medical Device Technology
Background:
- Intramedullary pressure during intraosseous (IO) procedures is linked to complications like bone marrow fat intravasation and pain.
- Understanding pressure dynamics is crucial for safe and effective IO access.
Purpose of the Study:
- To quantify inter-provider variability in pressures generated during initial intraosseous flush procedures.
- To investigate the relationship between flush duration and resulting intramedullary pressure.
Main Methods:
- IO cannulas were placed in proximal tibiae and humeri of cadavers.
- Intramedullary pressures were recorded using a second cannula.
- Fifteen emergency physicians performed 60 flushes, with duration and pressure continuously monitored.
Main Results:
- Median IO pressure was 903 mm Hg (range: 83-2941 mm Hg); median flush duration was 5.2 seconds.
- Significant inter-provider variability in peak IO pressure was observed (P<.001).
- An inverse, nonlinear relationship existed between flush duration and peak IO pressure.
Conclusions:
- Physician performance during IO flushes shows significant variability in generated pressures.
- A 35-fold difference in flush forces highlights the need for standardization.
- Extending flush duration over several seconds may mitigate dangerously high intramedullary pressures.
More Related Videos
03:40Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
Published on: January 17, 2025
05:04Author Spotlight: Evaluating Clinicians' Adoption of Ultrasound-Guided Vascular Cannulation Through Simulation Training
Published on: August 9, 2024
Related Concept Videos
One-Compartment Open Model for IV Bolus Administration: Estimation of Clearance
In the one-compartment open model for intravenous (IV) bolus administration, clearance is estimated by dividing the elimination rate by the plasma drug concentration. This equation leverages the elimination rate constant and the apparent...
One-Compartment Open Model for IV Bolus Administration: General Considerations
The drug's presence in the body is defined by an equation representing the difference between the rates of drug entry and exit. Key parameters—elimination rate constant,...
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence
Pre-Procedural Guidelines for Assessing Blood Pressure
Hemodialysis II: Procedure and Complications
Endoscopic Procedures V: ERCP
Patient...