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Updated: May 1, 2026
Ultrathin Porated Elastic Hydrogels As a Biomimetic Basement Membrane for Dual Cell Culture
Published on: December 26, 2017
A novel poly(amido amine)-dendrimer-based hydrogel as a mimic for the extracellular matrix
Yao Wang1, Qiang Zhao, He Zhang
1Beijing National Laboratory for Molecular Sciences and the Key Laboratory of Polymer Chemistry and Physics of the Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.
Abstract:
The extracellular matrix is mimicked by a novel dendrimer-based hydrogel, which exhibits a highly interconnected porous network, enhanced mechanical stiffness, and a low swelling ratio. The hydrogel system supports the proliferation and differentiation of mesenchymal stem cells without any cytotoxic effects. This dendrimer-based hydrogel may serve as a model for developing new advanced materials with applications in tissue engineering.
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01:29The Extracellular Matrix
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01:42The Extracellular Matrix