Related Experiment Video
Updated: May 1, 2026
Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
Published on: March 14, 2013
Development of a near infrared multi-wavelength, multi-channel, time-resolved spectrometer for measuring brain tissue
Luke Dunne1, Jem Hebden2, Ilias Tachtsidis2
1Department of Medical Physics & Bioengineering, University College London, Malet Place Eng. Building, Gower Street, London, WC1E 6BT, UK. luke.dunne.10@ucl.ac.uk.
Abstract:
We present a novel time domain functional near infrared spectroscopy system using a supercontinuum laser allowing us to measure the coefficient of absorption and scattering of up to 16 multiplexed wavelengths in the near infrared region. This is a four detector system that generates up to 3 mW of light for each wavelength with a narrow 2-3 nm FWHM bandwidth between 650 and 890 nm; each measurement of 16 wavelengths per channel can be performed up to a rate of 1 Hz. We can therefore quantify absolute haemoglobin changes in tissue and are currently investigating which and how many wavelengths are needed to resolve additional chromophores in tissue, such as water and the oxidation state of cytochrome-c-oxidase.
More Related Videos
07:12Real-Time Monitoring of Neurocritical Patients with Diffuse Optical Spectroscopies
Published on: November 19, 2020
07:06Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging
Published on: May 7, 2017