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Vitamin D and neurocognitive function.

Mathias Schlögl1, Michael F Holick2

  • 1University Center for Medicine of Aging Basel, University of Basel, Basel, Switzerland.

Clinical Interventions in Aging
|April 15, 2014
PubMed
Summary
This summary is machine-generated.

Vitamin D deficiency is linked to cognitive decline and dementia, especially in older adults. More research is needed to confirm if vitamin D supplements can help prevent or treat these conditions.

Keywords:
25(OH)D levelAlzheimer’s diseasecognitionmild cognitive impairmentvascular dementiavitamin D

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Area of Science:

  • Neuroscience
  • Endocrinology
  • Gerontology

Background:

  • Emerging evidence links vitamin D to chronic illnesses beyond bone health, including neurocognitive decline.
  • Vitamin D deficiency is prevalent, particularly in developed nations, increasing disease risk.
  • Older adults face higher deficiency risk due to reduced skin synthesis and dietary intake.

Purpose of the Study:

  • To explore the association between vitamin D levels and cognitive function.
  • To highlight the need for interventions in mild cognitive impairment and dementia.

Main Methods:

  • Review of recent studies on vitamin D and cognitive health.
  • Identification of populations at high risk for vitamin D deficiency.

Main Results:

  • Studies confirm an association between cognitive impairment, dementia, and vitamin D deficiency.
  • Vitamin D's role in neurocognition is an area of growing research interest.

Conclusions:

  • Vitamin D deficiency is associated with cognitive decline and dementia.
  • Well-designed trials are needed to evaluate vitamin D and lifestyle interventions for mild cognitive impairment and dementia.