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Updated: May 1, 2026

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
Published on: May 4, 2021
Use of nitric oxide in thoracic surgery for a high risk cardiac patient
Vishal Garg1, Sameena Ahmed, Steven Stamenkovic
1Department of Cardiothoracic and Transplant Anaesthesia, Freeman Hospital, Newcastle Upon Tyne, United Kingdom.
Abstract:
Nitric oxide (NO) is a selective pulmonary vasodilator especially in the presence of pulmonary artery hypertension. With right ventricle (RV) dysfunction, inhaled NO may increase RV ejection fraction and cardiac output. The main advantage of NO over intravenous therapy is its inability to decrease systemic pressure thereby maintaining the coronary perfusion pressure and the myocardial perfusion. In this case report, we discuss the use of NO in a routine thoracic surgery patient suffering with severe left ventricular dysfunction and a potential candidate for a very high cardiac risk.
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